Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK71322.1Conserved hypothetical protein; Identified by match to protein family HMM PF00296. (284 aa)    
Predicted Functional Partners:
ABK72942.1
Monooxygenase; Identified by match to protein family HMM PF00296.
  
     0.760
cofD
Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.751
fbiB
F420-0:gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0. Is able to add up to six glutamates to F420-0, producing F420-3 as the major product with lesser amount of F420-4,5,6, consistent with it producing the polyglutamated F420 compounds present in Mycobacterium smegmatis. In the N-terminal section; belong [...]
 
  
 0.743
ABK70857.1
5,10-methylenetetrahydromethanopterin reductase.
  
    0.742
ABK70757.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
     0.736
ABK76006.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
  
     0.732
ABK75525.1
Identified by match to protein family HMM PF00296.
  
     0.730
ABK72224.1
5,10-methylenetetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296.
  
     0.726
ABK72268.1
N5,N10- methylenetetrahydromethanopterin reductase-related protein.
  
     0.717
ABK75024.1
Oxidoreductase; Identified by match to protein family HMM PF00296.
  
     0.714
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.