Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hydA-2Dihydropyrimidinase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02033. (487 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.924
ABK75477.1
N-carbamoyl-L-amino acid amidohydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01879.
 
 
 0.858
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.845
ABK75274.1
Hydrolase; Identified by match to protein family HMM PF00795.
 
 0.825
ABK70858.1
Globin; Identified by match to protein family HMM PF01152.
     
 0.774
ABK71848.1
N5,N10-methylene- tetrahydromethanopterin reductase; Identified by match to protein family HMM PF00296.
 
     0.770
ABK73964.1
Oxidoreductase; Identified by match to protein family HMM PF00296.
 
     0.770
carB
Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family.
  
 
 0.734
ABK74201.1
Integral membrane transporter; Identified by match to protein family HMM PF02133.
 
  
 0.734
carA
Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.
  
  
 0.713
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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