Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK69990.1Dihydropteroate synthase; Identified by match to protein family HMM PF00753. (321 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
    
 0.842
folP-2
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
    
 0.842
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.
     
  0.840
ABK69773.1
Muconolactone delta-isomerase; Identified by match to protein family HMM PF02426; Belongs to the muconolactone Delta-isomerase family.
  
    0.780
ABK75750.1
L-carnitine dehydratase/bile acid-inducible protein F; Identified by match to protein family HMM PF02515; Belongs to the CoA-transferase III family.
       0.777
ABK71380.1
Cyclase.
 
    0.678
ABK74498.1
GAF domain protein; Identified by match to protein family HMM PF01590.
       0.649
ABK70401.1
Sugar transporter, permease protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
       0.448
acpS
Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
    
  0.407
ABK73609.1
Identified by match to protein family HMM PF00753.
 
 
 0.402
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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