ABK76203.1 protein (Mycolicibacterium smegmatis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ABK76203.1

Identified by match to protein family HMM PF02629. (687 aa)

Predicted Functional Partners:

ABK76139.1

0.956

orB

0.923

sucB

0.921

pta

0.886

ABK71023.1

0.879

ABK73436.1

0.879

PrpE

0.866

acsA

0.862

ackA

0.858

ABK72864.1

0.851

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK71023.1	ABK72864.1	MSMEG_0309	MSMEG_4710	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	0.943
ABK71023.1	ABK76139.1	MSMEG_0309	MSMEG_4646	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Pyruvate synthase; Identified by match to protein family HMM PF01855.	0.508
ABK71023.1	ABK76203.1	MSMEG_0309	MSMEG_4075	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Identified by match to protein family HMM PF02629.	0.879
ABK71023.1	PrpE	MSMEG_0309	MSMEG_5404	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	propionate--CoA ligase; Identified by match to protein family HMM PF00501.	0.974
ABK71023.1	ackA	MSMEG_0309	MSMEG_0784	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.940
ABK71023.1	acsA	MSMEG_0309	MSMEG_6179	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.973
ABK71023.1	pta	MSMEG_0309	MSMEG_0783	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.946
ABK71023.1	sucB	MSMEG_0309	MSMEG_4283	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927.	0.424
ABK72864.1	ABK71023.1	MSMEG_4710	MSMEG_0309	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.943
ABK72864.1	ABK73436.1	MSMEG_4710	MSMEG_5859	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	0.943
ABK72864.1	ABK76139.1	MSMEG_4710	MSMEG_4646	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Pyruvate synthase; Identified by match to protein family HMM PF01855.	0.818
ABK72864.1	ABK76203.1	MSMEG_4710	MSMEG_4075	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Identified by match to protein family HMM PF02629.	0.851
ABK72864.1	PrpE	MSMEG_4710	MSMEG_5404	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	propionate--CoA ligase; Identified by match to protein family HMM PF00501.	0.943
ABK72864.1	ackA	MSMEG_4710	MSMEG_0784	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.459
ABK72864.1	acsA	MSMEG_4710	MSMEG_6179	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.	0.943
ABK72864.1	orB	MSMEG_4710	MSMEG_4645	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Alpha oxoglutarate ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775.	0.811
ABK72864.1	pta	MSMEG_4710	MSMEG_0783	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.973
ABK72864.1	sucB	MSMEG_4710	MSMEG_4283	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR02927.	0.799
ABK73436.1	ABK72864.1	MSMEG_5859	MSMEG_4710	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	0.943
ABK73436.1	ABK76139.1	MSMEG_5859	MSMEG_4646	Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.	Pyruvate synthase; Identified by match to protein family HMM PF01855.	0.508