Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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menB-2Naphthoate synthase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)    
Predicted Functional Partners:
menD
2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
  
 0.962
ABK71168.1
O-succinylbenzoic acid--CoA ligase; Identified by match to protein family HMM PF00501.
 
 
 0.954
ABK75683.1
ComA operon protein 2; Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369.
 
  
 0.906
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
  
 0.866
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
  
  
 
0.863
ABK76046.1
cyclohexanecarboxylate-CoA ligase; Identified by match to protein family HMM PF00501.
 
 
 0.845
ABK72571.1
acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF08028.
    
 0.804
ABK70332.1
3-hydroxybutyryl-CoA dehydratase; Identified by match to protein family HMM PF00378.
 
   
0.798
ABK71837.1
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
  
 0.792
ABK71555.1
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
  
 0.788
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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