Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ABK75603.1Possible lysine decarboxylase superfamily protein; Identified by match to protein family HMM PF03641; Belongs to the LOG family. (183 aa)    
Predicted Functional Partners:
ABK74333.1
dTDP-glucose 4,6-dehydratase.
  
    0.689
ABK69781.1
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.667
ABK69864.1
Probable ferredoxin/ferredoxin--NADP reductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF07992.
    
  0.666
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.559
nrdE1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family.
  
    0.430
ABK70217.1
Ribonucleoside-diphosphate reductase, alpha subunit; Identified by match to protein family HMM PF00317; match to protein family HMM PF02867; match to protein family HMM TIGR02506.
  
    0.430
nrdB
Ribonucleoside-diphosphate reductase, beta subunit; Probable oxidase that might be involved in lipid metabolism. Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
  
    0.428
ABK72117.1
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
    0.428
ABK71415.1
Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268.
  
    0.428
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.424
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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