Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74773.1Phosphoglycolate phosphatase, chromosomal; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. (225 aa)    
Predicted Functional Partners:
ABK76023.1
tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
      0.853
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.828
ABK71774.1
Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.
  
 
 0.791
ABK75395.1
Conserved hypothetical protein.
  
    0.746
ABK75631.1
Arabinose-proton symporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
 0.639
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
  
  
 0.634
hisE
phosphoribosyl-ATP pyrophosphohydrolase; Identified by match to protein family HMM PF01503.
     
 0.624
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
  
 0.575
ABK74994.1
Dtdp-glucose-46-dehydratase.
  
    0.573
ABK70529.1
Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
  
 0.565
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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