node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK74288.1 | ABK75845.1 | MSMEG_4192 | MSMEG_4190 | Conserved hypothetical protein. | Identified by match to protein family HMM PF00459. | 0.761 |
ABK74288.1 | cysS | MSMEG_4192 | MSMEG_4189 | Conserved hypothetical protein. | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | 0.793 |
ABK74288.1 | mca | MSMEG_4192 | MSMEG_5261 | Conserved hypothetical protein. | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics. Activity is specific for the mycothiol moiety. | 0.589 |
ABK74288.1 | mshA | MSMEG_4192 | MSMEG_0933 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway; Belongs to the glycosyltransferase group 1 family. MshA subfamily. | 0.450 |
ABK74288.1 | mshB | MSMEG_4192 | MSMEG_5129 | Conserved hypothetical protein. | N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha- D-Glucopyranoside Deacetylase MshB; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.666 |
ABK75845.1 | ABK74288.1 | MSMEG_4190 | MSMEG_4192 | Identified by match to protein family HMM PF00459. | Conserved hypothetical protein. | 0.761 |
ABK75845.1 | cysS | MSMEG_4190 | MSMEG_4189 | Identified by match to protein family HMM PF00459. | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | 0.783 |
ABK76208.1 | cysS | MSMEG_6092 | MSMEG_4189 | Lsr2 protein. | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | 0.776 |
ABK76208.1 | glmM | MSMEG_6092 | MSMEG_1559 | Lsr2 protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.777 |
ABK76208.1 | rpoZ | MSMEG_6092 | MSMEG_3053 | Lsr2 protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.810 |
cysS | ABK74288.1 | MSMEG_4189 | MSMEG_4192 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Conserved hypothetical protein. | 0.793 |
cysS | ABK75845.1 | MSMEG_4189 | MSMEG_4190 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Identified by match to protein family HMM PF00459. | 0.783 |
cysS | ABK76208.1 | MSMEG_4189 | MSMEG_6092 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Lsr2 protein. | 0.776 |
cysS | glmM | MSMEG_4189 | MSMEG_1559 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.806 |
cysS | gpgS | MSMEG_4189 | MSMEG_5084 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Glycosyl transferase, group 2 family protein; Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs). Catalyzes the transfer of a glucose (Glc) moiety from uridine diphosphate (UDP-Glc) to the position 2 of 3-phospho-D-glycerate (3- PGA) to form glucosyl-3-phosphoglycerate (GPG). It can use UDP-glucose, ADP-glucose and GDP-glucose as donor substrates with decreasing affinity, and 3-PGA as an acceptor. D-glycerate could only be the acceptor with ADP- glucose and at a very low rate. | 0.776 |
cysS | mca | MSMEG_4189 | MSMEG_5261 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics. Activity is specific for the mycothiol moiety. | 0.960 |
cysS | mshA | MSMEG_4189 | MSMEG_0933 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | Conserved hypothetical protein; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway; Belongs to the glycosyltransferase group 1 family. MshA subfamily. | 0.970 |
cysS | mshB | MSMEG_4189 | MSMEG_5129 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha- D-Glucopyranoside Deacetylase MshB; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.973 |
cysS | rpoZ | MSMEG_4189 | MSMEG_3053 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.817 |
cysS | thrS | MSMEG_4189 | MSMEG_2931 | cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.780 |