node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71868.1 | ABK72054.1 | MSMEG_6272 | MSMEG_5442 | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.982 |
ABK71868.1 | ABK75920.1 | MSMEG_6272 | MSMEG_1574 | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | 0.911 |
ABK71868.1 | gdh | MSMEG_6272 | MSMEG_4699 | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | NAD-glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate. Highly specific for NAD. | 0.909 |
ABK71868.1 | glnA-2 | MSMEG_6272 | MSMEG_4290 | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.946 |
ABK71868.1 | nirB | MSMEG_6272 | MSMEG_0427 | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | Nitrite reductase [NAD(P)H], large subunit; Identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.907 |
ABK72054.1 | ABK71868.1 | MSMEG_5442 | MSMEG_6272 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | 0.982 |
ABK72054.1 | ABK75920.1 | MSMEG_5442 | MSMEG_1574 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | 0.918 |
ABK72054.1 | carB | MSMEG_5442 | MSMEG_3047 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.416 |
ABK72054.1 | gdh | MSMEG_5442 | MSMEG_4699 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate. Highly specific for NAD. | 0.961 |
ABK72054.1 | glnA-2 | MSMEG_5442 | MSMEG_4290 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.970 |
ABK72054.1 | glnD | MSMEG_5442 | MSMEG_2427 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.529 |
ABK72054.1 | nirB | MSMEG_5442 | MSMEG_0427 | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Nitrite reductase [NAD(P)H], large subunit; Identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.931 |
ABK73082.1 | glnA-2 | MSMEG_2426 | MSMEG_4290 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.934 |
ABK73082.1 | glnD | MSMEG_2426 | MSMEG_2427 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.999 |
ABK73082.1 | glnE | MSMEG_2426 | MSMEG_4293 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.782 |
ABK75920.1 | ABK71868.1 | MSMEG_1574 | MSMEG_6272 | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | NAD-glutamate dehydrogenase; Identified by match to protein family HMM PF05088. | 0.911 |
ABK75920.1 | ABK72054.1 | MSMEG_1574 | MSMEG_5442 | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | Glutamate dehydrogenase; Identified by match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.918 |
ABK75920.1 | gdh | MSMEG_1574 | MSMEG_4699 | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | NAD-glutamate dehydrogenase; Catalyzes the reversible conversion of L-glutamate to 2- oxoglutarate. Highly specific for NAD. | 0.911 |
ABK75920.1 | glnA-2 | MSMEG_1574 | MSMEG_4290 | Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family. | Glutamine synthetase, type I; Involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. | 0.923 |
carA | carB | MSMEG_3046 | MSMEG_3047 | Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.999 |