Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72969.1Protease; Identified by match to protein family HMM PF00561. (510 aa)    
Predicted Functional Partners:
ABK70911.1
Acyltransferase, ws/dgat/mgat subfamily protein; Identified by match to protein family HMM PF03007; match to protein family HMM TIGR02946; Belongs to the long-chain O-acyltransferase family.
       0.713
ABK73832.1
Conserved hypothetical protein.
  
     0.678
ABK70103.1
Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801.
  
 
 0.677
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
   
 0.593
ABK71854.1
Putative long-chain fatty-acid--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01746.
  
 0.587
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
  
 0.567
ABK73866.1
Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561.
 
    
0.518
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
   
 0.497
pks5
Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.
  
 0.495
ABK70529.1
Mycocerosic acid synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801.
  
 0.474
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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