Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72727.1Transcription regulator AmtR; Identified by match to protein family HMM PF00440. (225 aa)    
Predicted Functional Partners:
ABK70291.1
enoyl-CoA hydratase/isomerase; Identified by match to protein family HMM PF00378.
  
 
 0.810
ABK75633.1
acyl-CoA synthase; Identified by match to protein family HMM PF00501.
     
 0.777
ABK74988.1
Transcriptional regulatory protein; Identified by match to protein family HMM PF00486.
      
 0.770
glnD
protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
      
 0.656
ABK71104.1
Urea amidolyase; Identified by match to protein family HMM PF02626; match to protein family HMM PF02682; match to protein family HMM TIGR00724.
 
   
 0.625
ABK74496.1
uroporphyrinogen-III synthetase; Identified by match to protein family HMM PF00486; match to protein family HMM PF02602.
      
 0.517
ABK70961.1
Adenylate cyclase, putative; Identified by match to protein family HMM PF01928; match to protein family HMM PF05235.
       0.504
ABK75042.1
Copper methylamine oxidase; Identified by match to protein family HMM PF01179; match to protein family HMM PF02727; match to protein family HMM PF02728.
      
 0.493
ABK73622.1
Conserved hypothetical protein.
 
     0.462
ABK70676.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
     0.443
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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