Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK70961.1Adenylate cyclase, putative; Identified by match to protein family HMM PF01928; match to protein family HMM PF05235. (508 aa)    
Predicted Functional Partners:
ABK75633.1
acyl-CoA synthase; Identified by match to protein family HMM PF00501.
     
 0.905
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.762
ABK76136.1
Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672.
     
 0.667
ABK70558.1
Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211.
    
 0.609
ABK69636.1
Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211.
     
 0.609
ABK70064.1
Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211.
     
 0.603
ABK72645.1
Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672.
     
 0.599
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.593
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
     
 0.570
ABK70533.1
Integral membrane protein.
  
     0.568
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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