STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABK71684.1Serine/threonine-protein kinase PknD; Identified by match to protein family HMM PF00069. (525 aa)    
Predicted Functional Partners:
ABK75945.1
Identified by match to protein family HMM PF00481.
 
 
 0.893
ABK72306.1
Protein phosphatase 2C; Identified by match to protein family HMM PF00481.
 
 0.889
garA
Forkhead-associated protein; Involved in regulation of glutamate metabolism. Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd and Gdh.
 
 
 0.883
pknB
Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA.
 
 
0.736
ABK73969.1
FHA domain protein; Identified by match to protein family HMM PF00498.
 
 
 0.630
fhaB
FHA domain protein; Regulates growth and cell division. Probably required for divisomal protein assembly under oxidative stress.
 
 
 0.608
ABK70045.1
Formamidase; Identified by match to protein family HMM PF03069.
  
    0.511
ABK74109.1
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061.
  
 
 0.490
ABK71056.1
Cell cycle protein, FtsW/RodA/SpoVE family protein; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
  
 
 0.480
wag31
DivIVA protein; Important for maintaining cell shape and cell wall integrity by localizing peptidoglycan synthesis to the cell poles. Protects PbpB (PBP3, FtsI) from oxidative stress-induced cleavage. Belongs to the DivIVA family.
   
 
 0.471
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.