STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK76042.1Isochorismatase hydrolase; Identified by match to protein family HMM PF00857. (247 aa)    
Predicted Functional Partners:
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
     
 0.839
phd
Hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the bacteriostatic effect of cognate toxin Doc. In M.smegmatis 3 TA systems (VapB-VapC, MazE-MazF and Phd-Doc) may be involved in monitoring the nutritional supply and physiological state of the cell, linking catabolic with anabolic reactions.
      
 0.823
saeA
Hypothetical protein; May be involved in assembly of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Involved in DNA conjugation in recipient (MKD8) but not donor (mc(2)155) strain.
  
     0.644
ABK69959.1
Cutinase superfamily protein; Identified by match to protein family HMM PF01083.
 
    0.626
ABK75522.1
Conserved hypothetical protein; Identified by match to protein family HMM PF05976.
 
  
 0.621
ABK75772.1
Conserved hypothetical protein.
  
    0.619
ABK76032.1
Conserved hypothetical protein.
 
    0.612
ABK75418.1
Carbohydrate kinase, PfkB, putative; Identified by match to protein family HMM PF00294.
 
  
 0.609
ABK74862.1
Conserved hypothetical protein.
 
   
 0.588
ABK75119.1
Acetylcholinesterase; Identified by match to protein family HMM PF00135; Belongs to the type-B carboxylesterase/lipase family.
     
 0.576
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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