Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72153.1Modulator of DNA gyrase; Identified by match to protein family HMM PF01523. (505 aa)    
Predicted Functional Partners:
ABK74071.1
CalR5 protein.
 
    0.968
egtB
Conserved hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. Cannot use the alternative thiols cysteine, N- acetylcysteine, or glutathione instead of gamma-glutamylcysteine as substrates, and histidine is a poor sulfur acceptor substrate compared to hercynine; Belongs to the EgtB family.
 
   
 0.723
ABK74797.1
Conserved hypothetical integral membrane protein; Identified by match to protein family HMM TIGR02206.
       0.682
pyrF
Orotidine 5'-phosphate decarboxylase; Identified by match to protein family HMM PF00215; match to protein family HMM TIGR02127; Belongs to the OMP decarboxylase family. Type 2 subfamily.
     
 0.680
cobM
Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family.
     
 0.675
ABK75315.1
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
  
 0.673
ABK70620.1
Endonuclease IV; Identified by match to protein family HMM PF01261; match to protein family HMM TIGR00587.
      
 0.669
ABK74386.1
Amidinotransferase; Identified by match to protein family HMM PF02274.
      
 0.669
ABK73233.1
ABC transporter, permease protein UspA; Identified by match to protein family HMM PF00528.
       0.626
ABK70185.1
Cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
    0.581
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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