Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75461.1Probable serine/threonine-protein kinase PknH, putative. (234 aa)    
Predicted Functional Partners:
ABK71123.1
LppR protein.
     
 0.687
ABK72306.1
Protein phosphatase 2C; Identified by match to protein family HMM PF00481.
  
 
 0.501
ABK75945.1
Identified by match to protein family HMM PF00481.
  
 
 0.501
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.494
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.487
ABK74109.1
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00498; match to protein family HMM PF01061.
  
 
 0.468
ABK71593.1
LprB protein.
   
  
 0.437
ABK73828.1
3-mercaptopyruvate sulfurtransferase; Identified by match to protein family HMM PF00581.
     
 0.425
ABK72203.1
Metallo-beta-lactamase superfamily protein; Identified by match to protein family HMM PF00753.
       0.413
ABK70355.1
Hydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389.
      
 0.412
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: medium (48%) [HD]