Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
ABK74424.1Identified by match to protein family HMM PF00128. (512 aa)    
Predicted Functional Partners:
mak
Trehalose synthase-fused probable maltokinase; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate (Probable). Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB.
 
 0.989
treS
Trehalose synthase; Catalyzes the reversible interconversion of maltose and trehalose by transglucosylation. Maltose is the preferred substrate. To a lesser extent, also displays amylase activity, catalyzing the endohydrolysis of (1->4)-alpha-D- glucosidic linkages in glycogen and maltooligosaccharides such as maltoheptaose, to produce maltose which then can be converted to trehalose. TreS plays a key role in the utilization of trehalose for the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P). Might also functio [...]
 
  
0.967
malQ
4-alpha-glucanotransferase; Identified by match to protein family HMM PF02446; match to protein family HMM TIGR00217.
  
 
 0.964
ABK74343.1
Alpha-amylase 3; Identified by match to protein family HMM PF00128.
 
  
0.954
ABK69530.1
Fructokinase; Identified by match to protein family HMM PF00294.
 
 
 0.951
ABK69877.1
Glucosidase; Identified by match to protein family HMM PF02056.
  
 
 0.943
ABK70975.1
Alpha-galactosidase; Identified by match to protein family HMM PF02056.
  
 
 0.940
ABK72717.1
Identified by match to protein family HMM PF01152.
      0.940
ABK71329.1
Identified by match to protein family HMM PF00232.
 
 
 0.936
ABK74482.1
PTS system, glucose-specific IIBC component; Identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826.
  
 
 0.900
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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