Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK71302.16-phosphogluconate dehydrogenase, NAD-binding; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807. (263 aa)    
Predicted Functional Partners:
ABK72245.1
6-phosphogluconate dehydrogenase, NAD-binding; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807.
 
 
 
0.980
mmsA
Methylmalonate-semialdehyde dehydrogenase; Identified by similarity to GB:AAA99190.1; match to protein family HMM PF00171; match to protein family HMM TIGR01722.
 
 
 0.952
mmsA-2
Methylmalonate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722.
 
 
 0.952
mmsB
3-hydroxyisobutyrate dehydrogenase; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR01692; Belongs to the HIBADH-related family.
  
  
 
0.947
ABK71291.1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786.
  
 
 0.947
ABK75534.1
acyl-CoA oxidase; Identified by match to protein family HMM PF00441; match to protein family HMM PF01756; match to protein family HMM PF02770.
  
 
 0.944
PrpE
propionate--CoA ligase; Identified by match to protein family HMM PF00501.
  
 
 0.942
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.942
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.939
ABK74100.1
propionyl-CoA carboxylase beta chain; Identified by match to protein family HMM PF01039.
  
 
 0.939
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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