node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK71793.1 | ABK73669.1 | MSMEG_4892 | MSMEG_4891 | Conserved hypothetical protein. | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | 0.902 |
ABK71793.1 | ahpD | MSMEG_4892 | MSMEG_4890 | Conserved hypothetical protein. | Alkylhydroperoxidase, AhpD family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.853 |
ABK72436.1 | ABK72676.1 | MSMEG_6186 | MSMEG_1516 | Conserved hypothetical protein. | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | 0.579 |
ABK72436.1 | ABK72796.1 | MSMEG_6186 | MSMEG_0971 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.687 |
ABK72436.1 | ABK73669.1 | MSMEG_6186 | MSMEG_4891 | Conserved hypothetical protein. | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | 0.919 |
ABK72436.1 | rpoB | MSMEG_6186 | MSMEG_1367 | Conserved hypothetical protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.795 |
ABK72436.1 | sodC | MSMEG_6186 | MSMEG_0835 | Conserved hypothetical protein. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. | 0.753 |
ABK72436.1 | trxB | MSMEG_6186 | MSMEG_6933 | Conserved hypothetical protein. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.562 |
ABK72676.1 | ABK72436.1 | MSMEG_1516 | MSMEG_6186 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | Conserved hypothetical protein. | 0.579 |
ABK72676.1 | ABK72796.1 | MSMEG_1516 | MSMEG_0971 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | Conserved hypothetical protein. | 0.579 |
ABK72676.1 | ABK73669.1 | MSMEG_1516 | MSMEG_4891 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | 0.833 |
ABK72676.1 | ABK74492.1 | MSMEG_1516 | MSMEG_5786 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | Thiredoxin; Identified by match to protein family HMM PF00085. | 0.571 |
ABK72676.1 | rpoB | MSMEG_1516 | MSMEG_1367 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.432 |
ABK72676.1 | trxB | MSMEG_1516 | MSMEG_6933 | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.920 |
ABK72796.1 | ABK72436.1 | MSMEG_0971 | MSMEG_6186 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.687 |
ABK72796.1 | ABK72676.1 | MSMEG_0971 | MSMEG_1516 | Conserved hypothetical protein. | Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992. | 0.579 |
ABK72796.1 | ABK73669.1 | MSMEG_0971 | MSMEG_4891 | Conserved hypothetical protein. | Alkylhydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system. Does not however seem to play a role in det [...] | 0.919 |
ABK72796.1 | rpoB | MSMEG_0971 | MSMEG_1367 | Conserved hypothetical protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.794 |
ABK72796.1 | sodC | MSMEG_0971 | MSMEG_0835 | Conserved hypothetical protein. | Copper/zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. | 0.754 |
ABK72796.1 | trxB | MSMEG_0971 | MSMEG_6933 | Conserved hypothetical protein. | Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292. | 0.502 |