Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK69619.1Tetratricopeptide repeat domain protein; Identified by match to protein family HMM PF00085; match to protein family HMM PF07719. (296 aa)    
Predicted Functional Partners:
ABK72676.1
Thioredoxin reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00072; match to protein family HMM PF01266; match to protein family HMM PF07992.
  
 0.932
ABK73236.1
Conserved hypothetical protein.
   
 
 0.811
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
  
 0.772
ABK72744.1
Methyltransferase; Identified by match to protein family HMM PF03848; match to protein family HMM PF05724; match to protein family HMM PF07992.
  
 0.769
ribBA
Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.752
groL-3
Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family.
  
 
 0.721
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.683
hemD
uroporphyrinogen-III synthase; Identified by match to protein family HMM PF00590; match to protein family HMM PF02602.
  
  
 0.672
ABK75295.1
FAD dependent oxidoreductase; Identified by match to protein family HMM PF03486; match to protein family HMM PF07992.
  
 0.659
ABK71664.1
acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930.
     
 0.655
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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