STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75618.1DNA repair exonuclease; Identified by match to protein family HMM PF00149. (384 aa)    
Predicted Functional Partners:
ABK73081.1
Antigen 34 kDa.
  
 0.992
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.980
ABK70161.1
Conserved hypothetical protein.
 
 
 0.966
ABK71856.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00570; match to protein family HMM PF00580.
  
 0.964
recA
Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]
  
 0.886
ABK72031.1
5'-3' exonuclease; Identified by match to protein family HMM PF01367; match to protein family HMM PF02739.
  
 0.872
ABK72131.1
Putative helicase.
  
 0.859
recQ
ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00271.
  
 0.836
ABK70942.1
ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270.
  
 0.836
ABK73907.1
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614.
  
 0.836
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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