| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70064.1 | ABK70151.1 | MSMEG_5018 | MSMEG_4279 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.951 |
| ABK70064.1 | ABK72250.1 | MSMEG_5018 | MSMEG_0731 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Conserved hypothetical protein. | 0.935 |
| ABK70064.1 | ABK72645.1 | MSMEG_5018 | MSMEG_6154 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | 0.980 |
| ABK70064.1 | ABK75261.1 | MSMEG_5018 | MSMEG_4477 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Hydrolase, alpha/beta hydrolase fold family protein; Identified by match to protein family HMM PF00561. | 0.819 |
| ABK70064.1 | folE | MSMEG_5018 | MSMEG_6104 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.935 |
| ABK70064.1 | mazG | MSMEG_5018 | MSMEG_5422 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Transcriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. | 0.935 |
| ABK70064.1 | moaA | MSMEG_5018 | MSMEG_5698 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.939 |
| ABK70064.1 | ndk | MSMEG_5018 | MSMEG_4627 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.940 |
| ABK70064.1 | relA | MSMEG_5018 | MSMEG_2965 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.938 |
| ABK70064.1 | ribBA | MSMEG_5018 | MSMEG_3072 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.937 |
| ABK70151.1 | ABK70064.1 | MSMEG_4279 | MSMEG_5018 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.951 |
| ABK70151.1 | ABK72250.1 | MSMEG_4279 | MSMEG_0731 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Conserved hypothetical protein. | 0.716 |
| ABK70151.1 | ABK72645.1 | MSMEG_4279 | MSMEG_6154 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Adenylate cyclase, family protein 3; Identified by match to protein family HMM PF00211; match to protein family HMM PF00672. | 0.968 |
| ABK70151.1 | folE | MSMEG_4279 | MSMEG_6104 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.826 |
| ABK70151.1 | mazG | MSMEG_4279 | MSMEG_5422 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Transcriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. | 0.932 |
| ABK70151.1 | moaA | MSMEG_4279 | MSMEG_5698 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.860 |
| ABK70151.1 | ndk | MSMEG_4279 | MSMEG_4627 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.937 |
| ABK70151.1 | relA | MSMEG_4279 | MSMEG_2965 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.878 |
| ABK70151.1 | ribBA | MSMEG_4279 | MSMEG_3072 | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | Riboflavin biosynthesis protein ribAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.832 |
| ABK72250.1 | ABK70064.1 | MSMEG_0731 | MSMEG_5018 | Conserved hypothetical protein. | Adenylate and Guanylate cyclase catalytic domain protein; Identified by match to protein family HMM PF00211. | 0.935 |
