Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74375.1Conserved hypothetical protein TIGR00026; Identified by match to protein family HMM PF04075; match to protein family HMM TIGR00026. (149 aa)    
Predicted Functional Partners:
ABK73917.1
Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243.
  
   
 0.856
ABK76173.1
Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243.
  
   
 0.849
fgd
F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor. Exhibits nearly no activity with D-mannose-6- phosphate or D-fructose-6-phosphate as substrate. Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
  
   
 0.834
ABK70204.1
HIT family protein; Identified by match to protein family HMM PF01230.
       0.762
cofD
Lppg:fo 2-phospho-l-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
  
   
 0.760
ABK72130.1
FMN-dependent monooxygenase; Identified by match to protein family HMM PF00296.
  
     0.756
ABK76236.1
MmcI protein.
  
     0.756
ABK69720.1
Conserved hypothetical protein.
  
     0.754
ABK72517.1
FMN-dependent monooxygenase; Identified by match to protein family HMM PF00296.
  
     0.754
ABK71700.1
Identified by match to protein family HMM PF00903.
       0.751
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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