| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70516.1 | ABK71828.1 | MSMEG_5073 | MSMEG_5070 | Identified by match to protein family HMM PF01596; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Trypsin; Identified by match to protein family HMM PF00089. | 0.453 |
| ABK70516.1 | rseA | MSMEG_5073 | MSMEG_5071 | Identified by match to protein family HMM PF01596; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. | 0.429 |
| ABK70516.1 | sigE | MSMEG_5073 | MSMEG_5072 | Identified by match to protein family HMM PF01596; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Extracytoplasmic function alternative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released (By similarity). | 0.630 |
| ABK70516.1 | tatB | MSMEG_5073 | MSMEG_5069 | Identified by match to protein family HMM PF01596; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Sec-independent translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.477 |
| ABK71828.1 | ABK70516.1 | MSMEG_5070 | MSMEG_5073 | Trypsin; Identified by match to protein family HMM PF00089. | Identified by match to protein family HMM PF01596; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.453 |
| ABK71828.1 | ABK74955.1 | MSMEG_5070 | MSMEG_2752 | Trypsin; Identified by match to protein family HMM PF00089. | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.454 |
| ABK71828.1 | rseA | MSMEG_5070 | MSMEG_5071 | Trypsin; Identified by match to protein family HMM PF00089. | Conserved hypothetical protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. | 0.772 |
| ABK71828.1 | sigE | MSMEG_5070 | MSMEG_5072 | Trypsin; Identified by match to protein family HMM PF00089. | Extracytoplasmic function alternative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released (By similarity). | 0.609 |
| ABK71828.1 | tatB | MSMEG_5070 | MSMEG_5069 | Trypsin; Identified by match to protein family HMM PF00089. | Sec-independent translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.938 |
| ABK74955.1 | ABK71828.1 | MSMEG_2752 | MSMEG_5070 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Trypsin; Identified by match to protein family HMM PF00089. | 0.454 |
| ABK74955.1 | carD | MSMEG_2752 | MSMEG_6077 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions. | 0.902 |
| ABK74955.1 | rpoA | MSMEG_2752 | MSMEG_1524 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.974 |
| ABK74955.1 | rpoB | MSMEG_2752 | MSMEG_1367 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.982 |
| ABK74955.1 | rpoC | MSMEG_2752 | MSMEG_1368 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.970 |
| ABK74955.1 | rpoZ | MSMEG_2752 | MSMEG_3053 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.896 |
| ABK74955.1 | sigE | MSMEG_2752 | MSMEG_5072 | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Extracytoplasmic function alternative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released (By similarity). | 0.621 |
| carD | ABK74955.1 | MSMEG_6077 | MSMEG_2752 | Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions. | Sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.902 |
| carD | rpoA | MSMEG_6077 | MSMEG_1524 | Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.983 |
| carD | rpoB | MSMEG_6077 | MSMEG_1367 | Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription. | 0.993 |
| carD | rpoC | MSMEG_6077 | MSMEG_1368 | Transcriptional regulator, CarD family protein; Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for the stringent response to starvation, oxidative and genotoxic stresses as well as control of rRNA under normal growth conditions. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.987 |
