STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK71028.1Transmembrane transport protein; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)    
Predicted Functional Partners:
ABK75203.1
Putative integral membrane protein.
 
     0.954
ABK70848.1
Integral membrane protein; Identified by match to protein family HMM PF04341.
 
  
 0.938
ABK73543.1
DNA-binding response regulator, putative; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
 
     0.923
ABK73324.1
Sensor histidine kinase; Identified by similarity to GB:AAB48182.1; match to protein family HMM PF02518; match to protein family HMM PF06580.
 
     0.913
ABK72370.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.623
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.541
PrpE
propionate--CoA ligase; Identified by match to protein family HMM PF00501.
 
  
 0.533
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
  
 0.468
ABK70948.1
acetyl-CoA synthetase; Identified by match to protein family HMM PF00501.
  
  
 0.458
ABK73027.1
Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501.
  
  
 0.458
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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