STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72841.1Na+/solute symporter; Identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (543 aa)    
Predicted Functional Partners:
ABK70848.1
Integral membrane protein; Identified by match to protein family HMM PF04341.
 
  
 0.995
ABK70948.1
acetyl-CoA synthetase; Identified by match to protein family HMM PF00501.
  
  
 0.900
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.765
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.686
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.651
ABK72438.1
Major facilitator superfamily protein MFS_1; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
       0.598
ABK75359.1
malyl-CoA lyase; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.
   
  
 0.549
ABK72632.1
AMP-dependent synthetase and ligase; Identified by match to protein family HMM PF00501.
 
  
 0.549
ABK70590.1
malyl-CoA lyase; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.
   
  
 0.549
ABK75830.1
malyl-CoA lyase; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.
   
  
 0.549
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.