Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75100.1Integral membrane protein. (757 aa)    
Predicted Functional Partners:
ABK74045.1
Methyltransferase type 11.
 
  
 0.865
ABK71111.1
Regulatory protein, TetR; Identified by match to protein family HMM PF00440.
  
    0.812
ABK73105.1
Conserved hypothetical protein.
  
   
 0.531
ABK70784.1
DoxX subfamily protein, putative; Identified by match to protein family HMM PF07681.
  
    0.489
ABK73301.1
Conserved hypothetical protein.
  
     0.446
ABK71774.1
Polyketide synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.
   
 
 0.433
inhA
[NADH] enoyl-[acyl-carrier-protein] reductase; Enoyl-ACP reductase of the type II fatty acid syntase (FAS- II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans- enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates (By similarity). The mycobacterial FAS-II system utilizes th [...]
  
   
 0.416
ABK75288.1
Acyltransferase; Identified by match to protein family HMM PF01757.
  
   
 0.414
ABK73621.1
Ubiquinol-cytochrome c reductase cytochrome b subunit; Identified by match to protein family HMM PF00033.
      
 0.412
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: medium (44%) [HD]