node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK69903.1 | ABK72681.1 | MSMEG_3116 | MSMEG_2762 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | 0.916 |
ABK69903.1 | ABK74698.1 | MSMEG_3116 | MSMEG_4650 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Putative oxidoreductase YisS; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894. | 0.911 |
ABK69903.1 | hisB | MSMEG_3116 | MSMEG_3207 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | 0.453 |
ABK69903.1 | hisF | MSMEG_3116 | MSMEG_3211 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.465 |
ABK69903.1 | hisH | MSMEG_3116 | MSMEG_3208 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.432 |
ABK69903.1 | hisIE | MSMEG_3116 | MSMEG_3212 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.437 |
ABK69903.1 | impA | MSMEG_3116 | MSMEG_3210 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | 0.933 |
ABK69903.1 | ino1 | MSMEG_3116 | MSMEG_6904 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.972 |
ABK69903.1 | iolG | MSMEG_3116 | MSMEG_4666 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). | 0.912 |
ABK69903.1 | priA-2 | MSMEG_3116 | MSMEG_3209 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | Bifunctional HisA/TrpF protein; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. | 0.472 |
ABK72681.1 | ABK69903.1 | MSMEG_2762 | MSMEG_3116 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. | 0.916 |
ABK72681.1 | ABK74698.1 | MSMEG_2762 | MSMEG_4650 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Putative oxidoreductase YisS; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894. | 0.910 |
ABK72681.1 | hisB | MSMEG_2762 | MSMEG_3207 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475. | 0.459 |
ABK72681.1 | hisF | MSMEG_2762 | MSMEG_3211 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.473 |
ABK72681.1 | hisH | MSMEG_2762 | MSMEG_3208 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.437 |
ABK72681.1 | hisIE | MSMEG_2762 | MSMEG_3212 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | phosphoribosyl-AMP pyrophosphatase/phosphoribosyl-ATP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.444 |
ABK72681.1 | impA | MSMEG_2762 | MSMEG_3210 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Inositol monophosphate phosphatase; Catalyzes the dephosphorylation of inositol 1-phosphate (I-1- P) to yield free myo-inositol, a key metabolite in mycobacteria. | 0.932 |
ABK72681.1 | ino1 | MSMEG_2762 | MSMEG_6904 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Myo-inositol-1-phosphate synthase; Catalyzes the conversion of glucose 6-phosphate to 1D-myo- inositol 3-phosphate; Belongs to the myo-inositol 1-phosphate synthase family. | 0.972 |
ABK72681.1 | iolG | MSMEG_2762 | MSMEG_4666 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). | 0.912 |
ABK72681.1 | priA-2 | MSMEG_2762 | MSMEG_3209 | Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459. | Bifunctional HisA/TrpF protein; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. | 0.474 |