Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK72606.1 | mazG | MSMEG_5424 | MSMEG_5422 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | Transcriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. | 0.862 |
| ABK72606.1 | mfd | MSMEG_5424 | MSMEG_5423 | Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.852 |
| ABK74721.1 | ABK75325.1 | MSMEG_3634 | MSMEG_1603 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | 0.964 |
| ABK74721.1 | guaA | MSMEG_3634 | MSMEG_1610 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
| ABK74721.1 | guaB | MSMEG_3634 | MSMEG_1602 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.951 |
| ABK74721.1 | hpt | MSMEG_3634 | MSMEG_6110 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.931 |
| ABK74721.1 | mazG | MSMEG_3634 | MSMEG_5422 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Transcriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. | 0.909 |
| ABK74721.1 | ndk | MSMEG_3634 | MSMEG_4627 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.424 |
| ABK74721.1 | rdgB | MSMEG_3634 | MSMEG_4899 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.949 |
| ABK74721.1 | surE | MSMEG_3634 | MSMEG_6820 | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | Acid phosphatase SurE; Identified by match to protein family HMM PF01975; match to protein family HMM TIGR00087. | 0.920 |
| ABK75325.1 | ABK74721.1 | MSMEG_1603 | MSMEG_3634 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | 0.964 |
| ABK75325.1 | guaA | MSMEG_1603 | MSMEG_1610 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.997 |
| ABK75325.1 | guaB | MSMEG_1603 | MSMEG_1602 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.988 |
| ABK75325.1 | hpt | MSMEG_1603 | MSMEG_6110 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.915 |
| ABK75325.1 | mazG | MSMEG_1603 | MSMEG_5422 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Transcriptional regulator, MazG family protein; Required to maintain the full capacity of the mycobacteria to respond to oxidative stress via the degradation of the oxidation- induced damaged nucleotides. It hydrolyzes all canonical (d)NTPs, as well as the mutagenic dUTP and 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'- triphosphate (8-oxo-dGTP). Also involved in the transcriptional activation of RelA in response to oxidative stress. | 0.907 |
| ABK75325.1 | rdgB | MSMEG_1603 | MSMEG_4899 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.931 |
| ABK75325.1 | surE | MSMEG_1603 | MSMEG_6820 | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | Acid phosphatase SurE; Identified by match to protein family HMM PF01975; match to protein family HMM TIGR00087. | 0.916 |
| guaA | ABK74721.1 | MSMEG_1610 | MSMEG_3634 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Identified by match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01303. | 0.998 |
| guaA | ABK75325.1 | MSMEG_1610 | MSMEG_1603 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304; Belongs to the IMPDH/GMPR family. | 0.997 |
| guaA | guaB | MSMEG_1610 | MSMEG_1602 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
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