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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_0123Conserved hypothetical protein; Identified by similarity to GB:BAC52503.1; match to protein family HMM PF07958. (403 aa)    
Predicted Functional Partners:
MXAN_0122
Putative GTP cyclohydrolase II; Identified by similarity to SP:P17620; match to protein family HMM PF00925.
     0.991
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
   
 0.949
mmsA
Methylmalonate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722.
 
   
 0.809
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 
 0.801
ribE-2
Riboflavin synthase, alpha subunit; Identified by similarity to SP:P50854; match to protein family HMM PF00677; match to protein family HMM TIGR00187.
  
 
 0.698
ribE
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.684
MXAN_0125
Hypothetical protein; Identified by Glimmer2; putative.
       0.624
MXAN_5071
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.570
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.559
MXAN_0504
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.541
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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