close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_0390Putative regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions. (165 aa)    
Predicted Functional Partners:
MXAN_7251
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF07721.
     
 0.809
MXAN_0085
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.806
MXAN_1599
Putative methyltransferase; Identified by match to protein family HMM PF00891.
      
 0.806
MXAN_2099
Conserved hypothetical protein; Identified by similarity to GB:AAS69558.1.
      
 0.806
MXAN_0391
Oxidoreductase, aldo/keto reductase family; Identified by match to protein family HMM PF00248.
  
    0.753
MXAN_0049
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.640
aceA
Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.
 
  
 0.583
MXAN_1307
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.541
MXAN_7134
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.541
MXAN_0392
Hypothetical protein; Identified by Glimmer2; putative.
       0.516
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.