Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
MXAN_0615DNA ligase, ATP-dependent; Identified by similarity to SP:P44121; match to protein family HMM PF01068. (357 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.867
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.800
MXAN_1620
Putative DNA polymerase II; Identified by match to protein family HMM PF00136; match to protein family HMM PF03104.
  
 0.719
dpbF
DNA polymerase domain protein.
  
 0.719
MXAN_0614
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069.
       0.601
MXAN_0335
Identified by match to protein family HMM PF01367; match to protein family HMM PF02739.
  
 0.592
topB
DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056.
  
 
 0.545
idnK
Thermosensitive gluconokinase; Identified by similarity to SP:P39208; match to protein family HMM PF01202; match to protein family HMM TIGR01313.
       0.524
MXAN_1374
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.523
MXAN_2218
Oxidoreductase, 2OG-Fe(II) oxygenase family; Identified by match to protein family HMM PF03171.
  
     0.519
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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