Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MXAN_0644Peptidase, M1 (aminopeptidase N) family; Identified by match to protein family HMM PF01433; match to protein family HMM PF03130. (882 aa)    
Predicted Functional Partners:
MXAN_5440
Hypothetical protein; Identified by Glimmer2; putative.
  
  
  0.956
pepA
Cytosol aminopeptidase family protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.927
gshB
Glutathione synthase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; Belongs to the prokaryotic GSH synthase family.
 
  
 0.920
ggt
Gamma-glutamyltransferase; Identified by similarity to SP:P18956; match to protein family HMM PF01019; match to protein family HMM TIGR00066.
     
  0.900
MXAN_5806
Putative glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
MXAN_4593
Hypothetical protein; Identified by Glimmer2; putative.
    
 0.824
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.824
MXAN_2557
Peptidase, M50A (S2P protease) subfamily; Identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054.
     
 0.807
MXAN_2567
Peptidase, M50A (S2P protease) subfamily; Identified by match to protein family HMM PF02163.
     
 0.807
MXAN_0969
Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212.
   
 
  0.802
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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