| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MXAN_0858 | MXAN_1393 | MXAN_0858 | MXAN_1393 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | 0.720 |
| MXAN_0858 | MXAN_3606 | MXAN_0858 | MXAN_3606 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Putative sensor histidine kinase; Identified by match to protein family HMM PF02518. | 0.791 |
| MXAN_0858 | dnaJ | MXAN_0858 | MXAN_0750 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.798 |
| MXAN_0858 | dnaJ-2 | MXAN_0858 | MXAN_3292 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.772 |
| MXAN_0858 | groL | MXAN_0858 | MXAN_4467 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.708 |
| MXAN_0858 | groL-2 | MXAN_0858 | MXAN_4895 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.708 |
| MXAN_0858 | groS | MXAN_0858 | MXAN_4894 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.744 |
| MXAN_0858 | grpE | MXAN_0858 | MXAN_6672 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.796 |
| MXAN_0858 | grpE-2 | MXAN_0858 | MXAN_4331 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | 0.742 |
| MXAN_0858 | htpG | MXAN_0858 | MXAN_6051 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.715 |
| MXAN_1393 | MXAN_0858 | MXAN_1393 | MXAN_0858 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | 0.720 |
| MXAN_1393 | dnaJ | MXAN_1393 | MXAN_0750 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.835 |
| MXAN_1393 | dnaJ-2 | MXAN_1393 | MXAN_3292 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...] | 0.684 |
| MXAN_1393 | groL | MXAN_1393 | MXAN_4467 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.714 |
| MXAN_1393 | groL-2 | MXAN_1393 | MXAN_4895 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.714 |
| MXAN_1393 | groS | MXAN_1393 | MXAN_4894 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.696 |
| MXAN_1393 | grpE | MXAN_1393 | MXAN_6672 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.638 |
| MXAN_1393 | grpE-2 | MXAN_1393 | MXAN_4331 | ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Identified by match to protein family HMM PF02518. | Putative co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of A [...] | 0.638 |
| MXAN_3606 | MXAN_0858 | MXAN_3606 | MXAN_0858 | Putative sensor histidine kinase; Identified by match to protein family HMM PF02518. | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | 0.791 |
| MXAN_3606 | dnaJ | MXAN_3606 | MXAN_0750 | Putative sensor histidine kinase; Identified by match to protein family HMM PF02518. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.779 |
STRING v12.5 is now available!
