close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_0966Lipoprotein, NLPA family; Identified by match to protein family HMM PF03180; Belongs to the nlpA lipoprotein family. (277 aa)    
Predicted Functional Partners:
MXAN_0967
Putative D-methionine ABC transporter, permease protein; Identified by similarity to SP:Q9KTJ6; match to protein family HMM PF00528.
 0.999
metN
D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 0.998
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.607
metF
5,10-methylenetetrahydrofolate reductase; Identified by similarity to GB:AAF64321.1; match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.574
MXAN_4821
Sulfate ABC transporter, periplasmic sulfate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971.
  
  
 0.555
MXAN_0971
Aspartate kinase/homoserine dehydrogenase; Identified by similarity to SP:P00561; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF03447; match to protein family HMM TIGR00657.
  
  
 0.545
MXAN_0965
Conserved hypothetical protein; Identified by similarity to GB:AAS41196.1.
       0.529
cysD
Sulfate adenylyltransferase, small subunit; Identified by similarity to SP:P21156; match to protein family HMM PF01507; match to protein family HMM TIGR02039.
   
  
 0.522
MXAN_5503
Polar amino acid transport system substrate-binding protein; Identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726.
  
 
 0.517
MXAN_1973
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.496
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: very high (>100%) [HD]