close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_0970Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF03841. (366 aa)    
Predicted Functional Partners:
MXAN_2041
Putative cystathionine beta-synthase; Identified by similarity to GB:AAG48621.1; match to protein family HMM PF00291; match to protein family HMM PF00571.
 0.988
MXAN_0971
Aspartate kinase/homoserine dehydrogenase; Identified by similarity to SP:P00561; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF03447; match to protein family HMM TIGR00657.
 
 
 0.980
MXAN_0969
Cys/Met metabolism PLP-dependent enzyme; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212.
 
  
 
0.977
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.973
MXAN_4171
Putative cysteine synthase; Identified by match to protein family HMM PF00291.
 0.967
MXAN_0992
Putative cysteine synthase; Identified by similarity to GB:AAG01804.1; match to protein family HMM PF00291.
 0.964
cysK
Cysteine synthase A; Identified by similarity to SP:P37887; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.960
MXAN_2278
Aspartate kinase/homoserine dehydrogenase; Identified by similarity to SP:P00561; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657.
 
 
 0.937
cysI
Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.932
metXA
Putative homoserine-O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
  
 0.925
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.