Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MXAN_1134Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211. (433 aa)    
Predicted Functional Partners:
MXAN_6298
GAF domain protein; Identified by match to protein family HMM PF01590.
     0.968
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.901
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
MXAN_4741
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
  0.900
MXAN_1918
Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027.
 
 
 0.818
MXAN_2955
Putative GTP cyclohydrolase I; Identified by similarity to SP:P19465; match to protein family HMM PF01227.
     
  0.800
MXAN_1953
Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027.
 
   0.770
MXAN_3837
Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027.
 
   0.764
MXAN_7041
Cyclic nucleotide-binding domain protein; Identified by match to protein family HMM PF00027.
 
   0.764
MXAN_4188
Adenylate/guanylate cyclase domain protein; Identified by match to protein family HMM PF00211.
  
     0.733
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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