STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_1144TPR domain protein; Identified by match to protein family HMM PF07719. (276 aa)    
Predicted Functional Partners:
MXAN_1145
DnaJ domain/tetratricopeptide repeat domain protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF00515; match to protein family HMM PF07719.
       0.731
MXAN_1143
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
     
 0.685
MXAN_1142
Hypothetical protein; Identified by Glimmer2; putative.
       0.642
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
    0.586
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
   
    0.491
MXAN_1141
Peptidase, M16 (pitrilysin) family; Identified by match to protein family HMM PF00478; match to protein family HMM PF00675; match to protein family HMM PF05193.
       0.477
MXAN_1146
Conserved hypothetical protein; Identified by match to protein family HMM PF07811.
       0.434
MXAN_1147
Hypothetical protein; Identified by Glimmer2; putative.
       0.434
MXAN_1148
Hypothetical protein; Identified by Glimmer2; putative.
       0.434
MXAN_1149
Hypothetical protein; Identified by Glimmer2; putative.
       0.434
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.