close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasRSigma-54 dependent DNA-binding response regulator SasR; Identified by similarity to GB:AAG45333.1; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (477 aa)    
Predicted Functional Partners:
sasS
Developmental sensor histidine kinase SasS; Identified by similarity to GB:AAB94883.1; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.881
sasN
Developmental regulator SasN; Identified by similarity to GB:AAC98284.1.
     
 0.807
mrpA
Sensor histidine kinase MrpA; Identified by similarity to GB:AAF99324.1; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
  0.743
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.742
MXAN_4262
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 0.738
MXAN_6015
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
  
  0.727
MXAN_1077
Sensory box histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
  
  
  0.723
frgB
Sensor histidine kinase FrgB; Identified by similarity to GB:AAF18102.1; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
  0.723
MXAN_0459
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  0.721
MXAN_4197
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
  0.709
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (38%) [HD]