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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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MXAN_1620Putative DNA polymerase II; Identified by match to protein family HMM PF00136; match to protein family HMM PF03104. (804 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.956
dinB
Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
   
 0.842
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.836
MXAN_3990
Conserved hypothetical protein; Identified by similarity to PIR:F98329.
   
 0.830
topB
DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056.
  
 0.822
MXAN_2148
Helicase, DEAD/DEAH family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
  
 
 
 0.771
MXAN_0615
DNA ligase, ATP-dependent; Identified by similarity to SP:P44121; match to protein family HMM PF01068.
  
 0.719
MXAN_0335
Identified by match to protein family HMM PF01367; match to protein family HMM PF02739.
  
 0.711
MXAN_6074
DNA ligase, ATP-dependent; Identified by match to protein family HMM PF01068; match to protein family HMM PF04675; match to protein family HMM PF04679.
   
 0.679
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.667
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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