STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mglAGliding motility protein MglA; Required for multicellular development and for both mechanisms of gliding: social (S) and adventurous (A) motility. Acts as an intracellular switch to coordinate A and S motilities. Controls the direction of gliding and gliding speed; Belongs to the small GTPase superfamily. Arf family. MglA subfamily. (195 aa)    
Predicted Functional Partners:
mglB
Gliding motility protein MglB; Identified by similarity to GB:AAA25388.2; match to protein family HMM PF03259.
 
 
 0.999
aglZ
Adventurous gliding motility protein AglZ; Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole.
    
 
 0.955
MXAN_5770
Conserved hypothetical protein; Identified by similarity to GB:AAR35399.1.
 
 
 0.928
frzS
Response regulator FrzS; Identified by similarity to GB:AAC98490.1; match to protein family HMM PF00072.
    
 
 0.887
frzZ
Response regulator FrzZ; Identified by similarity to GB:AAC44537.1; match to protein family HMM PF00072.
      
 0.790
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
  
 0.775
MXAN_4739
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.750
MXAN_5196
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.750
masK
masK protein; Essential for growth. Interacts with MglA to control social gliding motility.
     
 0.743
MXAN_5766
TPR domain protein; Identified by match to protein family HMM PF00515.
  
  
 0.742
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.