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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_1970Transcriptional regulator, ArsR family; Identified by match to protein family HMM PF01022; match to protein family HMM PF01209; match to protein family HMM PF05175. (298 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.750
MXAN_1969
Identified by match to protein family HMM PF01734.
       0.578
MXAN_3779
Non-ribosomal peptide synthetase/polyketide synthase; Identified by similarity to GB:AAF15891.2; match to protein family HMM PF00109; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801; match to protein family HMM TIGR01733.
   
 
0.500
MXAN_3634
Non-ribosomal peptide synthase; Identified by match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733.
     
 0.446
MXAN_4532
Non-ribosomal peptide synthase; Identified by similarity to PIR:T18551; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733.
     
 0.446
topA
Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...]
     
 0.445
birA
BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.445
MXAN_6735
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01590; match to protein family HMM PF02518.
  
  
 0.430
MXAN_4402
Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.
     
 0.408
MXAN_0787
Helicase, DEAD/DEAH family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01230; match to protein family HMM PF04851; Belongs to the peptidase S24 family.
   
 
 0.405
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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