| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MXAN_0024 | MXAN_5981 | MXAN_0024 | MXAN_5981 | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | 0.740 |
| MXAN_0024 | rnr | MXAN_0024 | MXAN_4210 | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.937 |
| MXAN_0024 | rph | MXAN_0024 | MXAN_2004 | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.915 |
| MXAN_2005 | rph | MXAN_2005 | MXAN_2004 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.990 |
| MXAN_5981 | MXAN_0024 | MXAN_5981 | MXAN_0024 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | 0.740 |
| MXAN_5981 | rnr | MXAN_5981 | MXAN_4210 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.740 |
| MXAN_5981 | rph | MXAN_5981 | MXAN_2004 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.988 |
| MXAN_5981 | rpsD | MXAN_5981 | MXAN_3325 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.850 |
| MXAN_5981 | rpsD-2 | MXAN_5981 | MXAN_6805 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.850 |
| MXAN_5981 | rpsE | MXAN_5981 | MXAN_3316 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.858 |
| MXAN_5981 | rpsK | MXAN_5981 | MXAN_3324 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.930 |
| MXAN_5981 | rtcA | MXAN_5981 | MXAN_3809 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | RNA 3'-terminal phosphate cyclase; Identified by similarity to SP:P46849; match to protein family HMM PF01137; match to protein family HMM PF05189. | 0.892 |
| MXAN_5981 | rtcA-2 | MXAN_5981 | MXAN_4981 | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.892 |
| rnr | MXAN_0024 | MXAN_4210 | MXAN_0024 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | 0.937 |
| rnr | MXAN_5981 | MXAN_4210 | MXAN_5981 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | 0.740 |
| rnr | rph | MXAN_4210 | MXAN_2004 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.915 |
| rph | MXAN_0024 | MXAN_2004 | MXAN_0024 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 3'-5' exoribonuclease, VacB/RNase II family; Identified by match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; Belongs to the RNR ribonuclease family. | 0.915 |
| rph | MXAN_2005 | MXAN_2004 | MXAN_2005 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.990 |
| rph | MXAN_5981 | MXAN_2004 | MXAN_5981 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Putative ribonuclease D; Identified by match to protein family HMM PF00570; match to protein family HMM PF01612. | 0.988 |
| rph | rnr | MXAN_2004 | MXAN_4210 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.915 |
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