close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_2588rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237. (399 aa)    
Predicted Functional Partners:
moaDE
Molybdopterin converting factor, subunits 1/2; Identified by match to protein family HMM PF02391; match to protein family HMM PF02597; match to protein family HMM TIGR01682.
 0.967
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.917
MXAN_4067
Identified by match to protein family HMM PF02597.
 
 
 0.874
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
 
 0.790
MXAN_2983
Putative cysteine desulfurase; Identified by similarity to SP:P05341; match to protein family HMM PF00266; match to protein family HMM PF01212.
   
 0.789
iscS
Putative cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.789
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.783
MXAN_2587
Conserved hypothetical protein; Identified by similarity to GB:AAQ57912.1.
     
 0.767
MXAN_4068
Conserved hypothetical protein, UPF0033 family; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family.
 
  
 0.748
MXAN_3779
Non-ribosomal peptide synthetase/polyketide synthase; Identified by similarity to GB:AAF15891.2; match to protein family HMM PF00109; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801; match to protein family HMM TIGR01733.
  
 
 0.721
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (20%) [HD]