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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_2626DNA internalization-related competence protein ComEC/Rec2; Identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361. (822 aa)    
Predicted Functional Partners:
MXAN_1199
Competence protein F, truncated.
 
  
 0.876
MXAN_2625
Hypothetical protein; Identified by Glimmer2; putative.
       0.782
MXAN_3105
Type IV leader peptidase family protein; Identified by match to protein family HMM PF01478.
 
  
 0.761
MXAN_1235
ComF domain protein.
 
  
 0.751
topA
Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...]
  
  
 0.749
pilC
Type 4 fimbrial assembly protein PilC; Identified by similarity to GB:AAA25733.1; similarity to GB:AAT00616.1; match to protein family HMM PF00482.
 
  
 0.745
gspO
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.744
MXAN_0712
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF01590; match to protein family HMM PF02518.
  
  
 0.729
gspF
General secretion pathway protein F; Identified by similarity to GB:AAD05175.1; match to protein family HMM PF00482; match to protein family HMM TIGR02120.
  
  
 0.709
radC
DNA repair protein RadC; Identified by similarity to SP:P25531; match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
 
  
 0.672
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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