STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (437 aa)    
Predicted Functional Partners:
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR01263.
 
 0.997
maiA
Maleylacetoacetate isomerase; Identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262.
 
 
 0.955
MXAN_2788
Rieske 2Fe-2S domain protein; Identified by match to protein family HMM PF00355.
 
    0.856
MXAN_5127
Aromatic amino acid hydroxylase, biopterin-dependent; Identified by match to protein family HMM PF00351.
 
  
 0.820
MXAN_6349
Putative fumarylacetoacetate hydrolase; Identified by match to protein family HMM PF01557.
 
  
 0.795
MXAN_0080
Conserved hypothetical protein; Identified by match to protein family HMM PF07287.
  
 
 0.775
MXAN_5926
Identified by match to protein family HMM PF01557.
  
  
 0.701
MXAN_6773
Putative pterin-4-alpha-carbinolamine dehydratase; Identified by match to protein family HMM PF01329.
  
  
 0.690
carD
Transcriptional regulator CarD; Identified by similarity to GB:CAA91224.1; match to protein family HMM PF02178; match to protein family HMM PF02559.
      
 0.674
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
 0.643
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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