| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MXAN_1105 | topA | MXAN_1105 | MXAN_3002 | Conserved hypothetical protein TIGR00253; Identified by similarity to GB:AAR34639.1; match to protein family HMM PF01985; match to protein family HMM TIGR00253. | Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...] | 0.848 |
| MXAN_1950 | recA | MXAN_1950 | MXAN_1388 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.655 |
| MXAN_1950 | recA-2 | MXAN_1950 | MXAN_1441 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.655 |
| MXAN_1950 | topA | MXAN_1950 | MXAN_3002 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614. | Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...] | 0.909 |
| MXAN_1950 | topB | MXAN_1950 | MXAN_0535 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614. | DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056. | 0.805 |
| MXAN_3917 | ssb | MXAN_3917 | MXAN_1071 | Glutamate synthase, large subunit; Identified by similarity to SP:P39812; similarity to SP:P55037; match to protein family HMM PF00310; match to protein family HMM PF00478; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.464 |
| MXAN_3917 | topA | MXAN_3917 | MXAN_3002 | Glutamate synthase, large subunit; Identified by similarity to SP:P39812; similarity to SP:P55037; match to protein family HMM PF00310; match to protein family HMM PF00478; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...] | 0.925 |
| MXAN_3917 | topB | MXAN_3917 | MXAN_0535 | Glutamate synthase, large subunit; Identified by similarity to SP:P39812; similarity to SP:P55037; match to protein family HMM PF00310; match to protein family HMM PF00478; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056. | 0.746 |
| MXAN_4839 | recA | MXAN_4839 | MXAN_1388 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.655 |
| MXAN_4839 | recA-2 | MXAN_4839 | MXAN_1441 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.655 |
| MXAN_4839 | topA | MXAN_4839 | MXAN_3002 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...] | 0.909 |
| MXAN_4839 | topB | MXAN_4839 | MXAN_0535 | ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR00614. | DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056. | 0.798 |
| leuS | leuS-2 | MXAN_4051 | MXAN_4745 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.906 |
| leuS | recA | MXAN_4051 | MXAN_1388 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.526 |
| leuS | recA-2 | MXAN_4051 | MXAN_1441 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.536 |
| leuS | topA | MXAN_4051 | MXAN_3002 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...] | 0.956 |
| leuS | topB | MXAN_4051 | MXAN_0535 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase III/ATP-dependent DNA helicase, RecQ family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR00614; match to protein family HMM TIGR01056. | 0.516 |
| leuS-2 | leuS | MXAN_4745 | MXAN_4051 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.906 |
| leuS-2 | recA | MXAN_4745 | MXAN_1388 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.532 |
| leuS-2 | recA-2 | MXAN_4745 | MXAN_1441 | leucyl-tRNA synthetase; Identified by similarity to SP:P07813; match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.512 |
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