close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
actBSigma-54 activator protein ActB; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (553 aa)    
Predicted Functional Partners:
actA
C-signal regulator ActA; Identified by similarity to GB:AAK38649.1; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
  
 0.805
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.726
MXAN_2445
Type III secretion system apparatus protein YscQ/HrcQ; Identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551.
  
  
 0.618
MXAN_5649
Type III secretion system apparatus protein YscQ/HrcQ; Identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551.
  
  
 0.618
MXAN_3215
ActC; Identified by similarity to GB:AAK38651.1; match to protein family HMM PF00583; match to protein family HMM PF01073; match to protein family HMM PF01370.
  
    0.606
mrpA
Sensor histidine kinase MrpA; Identified by similarity to GB:AAF99324.1; match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
 
 0.568
MXAN_3343
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF01590; match to protein family HMM PF02518.
 
 
 0.535
sasS
Developmental sensor histidine kinase SasS; Identified by similarity to GB:AAB94883.1; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.521
pilS
Pilin regulatory protein PilS; Identified by similarity to GB:AAB40880.1; match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 
 0.515
MXAN_0195
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM TIGR00229.
 
 
0.514
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.