Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ccmFCytochrome c-type biogenesis protein CcmF; Identified by match to protein family HMM PF01578. (673 aa)    
Predicted Functional Partners:
ccmE
Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
 
 
 0.995
ccmB
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.993
dsbE
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P33926.
  
 0.989
ccmC
Heme exporter protein CcmC; Identified by similarity to SP:P30962; match to protein family HMM PF01578.
 
  
 0.972
MXAN_3235
Cytochrome c-type biogenesis protein, CcmH/CycL/Ccl2/NrfF family; Possible subunit of a heme lyase.
 
  
 0.935
ccmA
Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
     0.818
MXAN_3255
Conserved hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
       0.773
MXAN_6156
Cytochrome c biogenesis protein/thioredoxin; Identified by match to protein family HMM PF00085; match to protein family HMM PF02683.
  
  
 0.712
MXAN_3251
Putative membrane protein.
       0.689
MXAN_2050
Response regulator; Identified by match to protein family HMM PF00072.
  
 
 0.668
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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