MXAN_3454 protein (Myxococcus xanthus) - STRING interaction network

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Score

MXAN_3454

2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198. (288 aa)

Predicted Functional Partners:

pdhB

0.995

pdhA

0.993

lpdA

0.976

MXAN_4565

0.973

MXAN_4217

0.968

citZ

0.962

gltA

0.962

sucC

0.933

pdhC

0.927

sucD

0.926

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MXAN_3454	MXAN_4217	MXAN_3454	MXAN_4217	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	0.968
MXAN_3454	MXAN_4565	MXAN_3454	MXAN_4565	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	2-oxoisovalerate dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:P37941; match to protein family HMM PF02779; match to protein family HMM PF02780.	0.973
MXAN_3454	citZ	MXAN_3454	MXAN_0407	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Citrate synthase; Identified by similarity to SP:P39120.	0.962
MXAN_3454	gltA	MXAN_3454	MXAN_3519	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.	0.962
MXAN_3454	lpdA	MXAN_3454	MXAN_4219	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	0.976
MXAN_3454	pdhA	MXAN_3454	MXAN_2666	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.993
MXAN_3454	pdhB	MXAN_3454	MXAN_2667	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.995
MXAN_3454	pdhC	MXAN_3454	MXAN_2668	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.927
MXAN_3454	sucC	MXAN_3454	MXAN_3541	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.933
MXAN_3454	sucD	MXAN_3454	MXAN_3542	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.926
MXAN_4217	MXAN_3454	MXAN_4217	MXAN_3454	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	2-oxo acid dehydrogenase acyltransferase catalytic domain protein; Identified by match to protein family HMM PF00198.	0.968
MXAN_4217	MXAN_4565	MXAN_4217	MXAN_4565	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	2-oxoisovalerate dehydrogenase complex, E1 component, beta subunit; Identified by similarity to SP:P37941; match to protein family HMM PF02779; match to protein family HMM PF02780.	0.990
MXAN_4217	citZ	MXAN_4217	MXAN_0407	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Citrate synthase; Identified by similarity to SP:P39120.	0.963
MXAN_4217	gltA	MXAN_4217	MXAN_3519	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family.	0.963
MXAN_4217	lpdA	MXAN_4217	MXAN_4219	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.	0.995
MXAN_4217	pdhA	MXAN_4217	MXAN_2666	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.994
MXAN_4217	pdhB	MXAN_4217	MXAN_2667	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.997
MXAN_4217	pdhC	MXAN_4217	MXAN_2668	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.917
MXAN_4217	sucC	MXAN_4217	MXAN_3541	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.939
MXAN_4217	sucD	MXAN_4217	MXAN_3542	Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.932